Article
Genetics of myasthenia gravis: a case-control association study in the Hellenic population.
Clinical & developmental immunology - 1 Jan 2012
Zagoriti Zoi, Georgitsi Marianthi, Giannakopoulou Olga, Ntellos Fotios, Tzartos Socrates J, Patrinos George P, Poulas Konstantinos
Abstract excerpt
Myasthenia gravis (MG) is an heterogeneous autoimmune disease characterized by the production of autoantibodies against proteins of the postsynaptic membrane, in the neuromuscular junction. The contribution of genetic factors to MG susceptibility has been evaluated through family and twin studies however, the precise genetic background of the disease remains elusive. We conducted a case-control association study...
Topics
- Adult
- Aged
- Case-Control Studies
- DNA-Binding Proteins
- Female
- Genetic Predisposition to Disease
- Genotype
- Greece
- Humans
- Interferon Regulatory Factors
- Interleukin-10
- Intracellular Signaling Peptides and Proteins
- Male