Article
A novel galectin-1 and interleukin 2 receptor β haplotype is associated with autoimmune myasthenia gravis.
Journal of neuroimmunology - 15 Dec 2010
Pál Zsuzsanna, Antal Péter, Millinghoffer András, Hullám Gábor, Pálóczi Krisztina, Tóth Sára, Gabius Hans-Joachim, Molnár Mária Judit, Falus András, Buzás Edit Irén
Abstract excerpt
Galectin-1 (LGALS1) and interleukin receptor 2β (IL2Rβ) are regulators of T-cell activation. Here we evaluated the association of regulatory region polymorphisms of the LGALS1 (rs4820293, rs4820294) and IL2Rβ (rs743777, rs228941) genes in 146 Caucasian myasthenia gravis patients compared to 291 ethnically matched controls. A significant difference was found in the distribution of the rs4820293/...
