Article
Isolation of synthetic lethal mutants of ras1 in Schizosaccharomyces pombe.
Molecules and cells - 31 Dec 1997
Chung K S, Kim K W, Yoo H S
Abstract excerpt
Ras proteins are membrane-associated guanine nucleotide-binding proteins that serve as molecular switches for signal transduction pathways in a diverse array of organisms. Various cellular factors are known to interact with Ras proteins. In order to find the novel cellular factors that are associated with Ras function, we have constructed synthetic lethal mutants of the ras1+ gene in Schizosaccharomyces pombe and...
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