Article
A novel gene, msa1, inhibits sexual differentiation in Schizosaccharomyces pombe.
Genetics - 1 May 2004
Jeong Hee Tae, Ozoe Fumiyo, Tanaka Katsunori, Nakagawa Tsuyoshi, Matsuda Hideyuki, Kawamukai Makoto
Abstract excerpt
Sexual differentiation in the fission yeast Schizosaccharomyces pombe is triggered by nutrient starvation or by the presence of mating pheromones. We identified a novel gene, msa1, which encodes a 533-aa putative RNA-binding protein that inhibits sexual differentiation. Disruption of the msa1 gene caused cells to hypersporulate. Intracellular levels of msa1 RNA and Msa1 protein diminished after several hours of...
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