Article
Two types of RAS mutants that dominantly interfere with activators of RAS.
Molecular and cellular biology - 1 Jun 1994
Jung V, Wei W, Ballester R, Camonis J, Mi S, Van Aelst L, Wigler M, Broek D
Abstract excerpt
In the fission yeast Schizosaccharomyces pombe, ras1 regulates both sexual development (conjugation and sporulation) and cellular morphology. Two types of dominant interfering mutants were isolated in a genetic screen for ras1 mutants that blocked sexual development. The first type of mutation, a...
Topics
- Base Sequence
- Cloning, Molecular
- Conjugation, Genetic
- Fungal Proteins
- Genes, Fungal
- Genes, ras
- Genotype
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Oligodeoxyribonucleotides
- Plasmids
- Restriction Mapping
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Schizosaccharomyces