Article
The ras1 function of Schizosaccharomyces pombe mediates pheromone-induced transcription.
The EMBO journal - 1 Apr 1992
Nielsen O, Davey J, Egel R
Abstract excerpt
Loss of ras1+ function renders fission yeast cells unable to undergo morphological changes in response to mating pheromones, whereas cells carrying activated mutations in ras1 are hyper-responsive. This has led to the suggestion that the ras1 gene product plays a role in mating pheromone signal transduction. Using partially purified M factor we demonstrate that the mat1-Pm gene, which controls entry into meiosis,...
Topics
- Blotting, Northern
- Genes, Fungal
- Genotype
- Mating Factor
- Mutation
- Peptides
- Pheromones
- RNA, Fungal
- Schizosaccharomyces
- Signal Transduction
- Temperature
- Transcription, Genetic