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Article

byr2, a Schizosaccharomyces pombe gene encoding a protein kinase capable of partial suppression of the ras1 mutant phenotype.

Molecular and cellular biology - 1 Jul 1991

Wang Y, Xu H P, Riggs M, Rodgers L, Wigler M

Abstract excerpt

Schizosaccharomyces pombe contains a single gene, ras1, which is a homolog of the mammalian RAS genes. ras1 is required for conjugation, sporulation, and normal cell shape. ras1 has been previously identified as ste5. We report here a gene we call byr2 that can encode a predicted protein kinase and can partially suppress defects in ras1 mutants. ras1 mutant strains expressing high levels of byr2 can sporulate...

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Identifiers

PMID: 2046669
DOI: 10.1128/mcb.11.7.3554-3563.1991
PMCID: PMC361098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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byr2, a Schizosaccharomyces pombe gene encoding a protein kinase capable of partial suppression of the ras1 mutant phenotype.PMID 2046669Read ↗

Identification of Ste4 as a potential regulator of Byr2 in the sexual response pathway of Schizosaccharomyces pombe.Semantic proximity Read ↗

Functional analysis of domains in the Byr2 kinase.Semantic proximity Read ↗

Mutational analyses of the interacting domains of Schizosaccharomyces pombe Byr2 with 14-3-3s.Semantic proximity Read ↗

The Byr2 kinase translocates to the plasma membrane in a Ras1-dependent manner.Semantic proximity Read ↗

Schizosaccharomyces pombe ras1 and byr1 are functionally related genes of the ste family that affect starvation-induced transcription of mating-type genes.Semantic proximity Read ↗

Bob1, a Gim5/MM-1/Pfd5 homolog, interacts with the MAP kinase kinase Byr1 to regulate sexual differentiation in the fission yeast, Schizosaccharomyces pombe.Semantic proximity Read ↗

Byr4, a dosage-dependent regulator of cytokinesis in S. pombe, interacts with a possible small GTPase pathway including Spg1 and Cdc16.Semantic proximity Read ↗

The Schizosaccharomyces pombe mra1 gene, which is required for cell growth and mating, can suppress the mating inefficiency caused by a deficit in the Ras1 activity.Semantic proximity Read ↗

Isolation of synthetic lethal mutants of ras1 in Schizosaccharomyces pombe.Semantic proximity Read ↗

Complementation of byr1 in fission yeast by mammalian MAP kinase kinase requires coexpression of Raf kinase.Semantic proximity Read ↗

Byr4 and Cdc16 form a two-component GTPase-activating protein for the Spg1 GTPase that controls septation in fission yeast.Semantic proximity Read ↗

Functional conservation between Schizosaccharomyces pombe ste8 and Saccharomyces cerevisiae STE11 protein kinases in yeast signal transduction.Semantic proximity Read ↗

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