Article
The contribution of host genetics to tuberculosis pathogenesis.
Kekkaku : [Tuberculosis] - 1 Jan 2011
Schurr Erwin
Abstract excerpt
Assessment of the contribution of host genetics to human tuberculosis is a long-standing research challenge. Evidence of genetic factors has come primarily from twin studies and risks to first-degree relatives of cases. In addition, inferences of strong genetic influences have come from anecdotal accounts of socially prominent families, population variation in TB incidence and susceptibility to infection, and...
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