Article
Evidence for a cluster of genes on chromosome 17q11-q21 controlling susceptibility to tuberculosis and leprosy in Brazilians.
Genes and immunity - 1 Jan 2004
Jamieson S E, Miller E N, Black G F, Peacock C S, Cordell H J, Howson J M M, Shaw M-A, Burgner D, Xu W, Lins-Lainson Z, Shaw J J, Ramos F, Silveira F, Blackwell J M
Abstract excerpt
The region of conserved synteny on mouse chromosome 11/human 17q11-q21 is known to carry a susceptibility gene(s) for intramacrophage pathogens. The region is rich in candidates including NOS2A, CCL2/MCP-1, CCL3/MIP-1alpha, CCL4/MIP-1beta, CCL5/RANTES, CCR7, STAT3 and STAT5A/5B. To examine the re...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
