Article
Identification of a domain within the human T-cell leukemia virus type 2 envelope required for syncytium induction and replication.
Journal of virology - 1 Mar 1998
Poon B, Chen I S
Abstract excerpt
In vitro infection by human T-cell leukemia virus type 1 and 2 (HTLV-1 and HTLV-2) can result in syncytium formation, facilitating viral entry. Using cell lines that were susceptible to HTLV-2-mediated syncytium formation but were nonfusogenic with HTLV-1, we constructed chimeric envelopes betwee...
Topics
- Binding Sites
- Cell Line
- Cell Membrane
- Gene Products, env
- Giant Cells
- HeLa Cells
- Human T-lymphotropic virus 2
- Humans
- Membrane Fusion
- Phenotype
- Recombinant Fusion Proteins
- Retroviridae Proteins, Oncogenic
- Viral Envelope Proteins
- Virus Replication
- env Gene Products, Human Immunodeficiency Virus