Article
The cytoplasmic domain of the human T-cell leukemia virus type I envelope can modulate envelope functions in a cell type-dependent manner.
Journal of virology - 1 Jan 1993
Pique C, Pham D, Tursz T, Dokhélar M C
Abstract excerpt
C-terminal truncations of the human T-cell leukemia virus type I envelope affected the intracellular maturation and syncytium formation in a cell type-dependent manner. The intracytoplasmic domain appears dispensable for syncytium formation, but its truncation can modulate the envelope functional...
Topics
- Cell Line
- DNA Mutational Analysis
- Gene Products, env
- Genetic Variation
- Human T-lymphotropic virus 1
- Humans
- Protein Conformation
- Retroviridae Proteins, Oncogenic
- Transfection
- Viral Envelope Proteins
- Viral Fusion Proteins