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Article

Role of the fusogenic peptide sequence in syncytium induction and infectivity of human immunodeficiency virus type 2.

Journal of virology - 1 Jul 1992

Steffy K R, Kraus G, Looney D J, Wong-Staal F

Abstract excerpt

Syncytium induction is a characteristic feature of infection by human immunodeficiency virus (HIV) in vitro. The hydrophobic amino terminus of the transmembrane glycoprotein of HIV type 1 is an essential determinant of virus entry into the target cell population and the formation of syncytia in cell culture. To define the role of the HIV type 2 fusion peptide during infection and syncytium formation, we...

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Identifiers

PMID: 1602558
DOI: 10.1128/JVI.66.7.4532-4535.1992
PMCID: PMC241263

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Role of the fusogenic peptide sequence in syncytium induction and infectivity of human immunodeficiency virus type 2.PMID 1602558Read ↗

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