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Article

Modulation of high affinity hormone binding. Human choriogonadotropin binding to the exodomain of the receptor is influenced by exoloop 2 of the receptor.

The Journal of biological chemistry - 13 Mar 1998

Ryu K, Lee H, Kim S, Beauchamp J, Tung C S, Isaacs N W, Ji I, Ji T H

Abstract excerpt

The lutropin/choriogonadotropin receptor is a seven-transmembrane receptor and consists of two major domains of similar size, an extracellular exodomain and a membrane-associated endodomain which includes 3 exoloops. The uniquely large exodomain is responsible for high affinity hormone binding whereas receptor activation occurs at the endodomain. However, little is known about the relationship between the...

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Identifiers

PMID: 9497355
DOI: 10.1074/jbc.273.11.6285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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