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Article

Two defective heterozygous luteinizing hormone receptors can rescue hormone action.

The Journal of biological chemistry - 3 May 2002

Lee ChangWoo, Ji Inhae, Ryu KiSung, Song YongSang, Conn P Michael, Ji Tae H

Abstract excerpt

Luteinizing hormone receptor is a G protein-coupled receptor and consists of two halves: the N-terminal extracellular half (exodomain) and C-terminal membrane-associated half (endodomain). Hormone binds to the exodomain, and the resulting hormone-exodomain complex modulates the endodomain to generate signals. There are mutations that impair either hormone binding or signal generation. We report that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11859079
DOI: 10.1074/jbc.M111818200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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