The tale of follitropin receptor diversity: a recipe for fine tuning gonadal responses?

doi:10.1016/j.mce.2005.11.052

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Article

The tale of follitropin receptor diversity: a recipe for fine tuning gonadal responses?

Molecular and cellular endocrinology - 2 Jan 2007

Sairam M Ram, Babu P Suresh

Abstract excerpt

The original concept (dogma) of a single FSH receptor entity coupling to G(s) protein to activate adenylate cyclase and producing cAMP as second messenger appears inadequate to explain pleiotropic actions of the hormone. The identification and expression of alternatively spliced gonadotropin receptors, suggest that alternative splicing could serve as a mechanism for creating receptor diversity. Studies focused on...

Topics

Alternative Splicing
Amino Acid Motifs
Amino Acid Sequence
Animals
Exons
Female
Genetic Variation
Gonadotropins
Gonads
Humans
Introns
Mice
Molecular Sequence Data
RNA, Messenger
Receptors, FSH
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 17081682
DOI: 10.1016/j.mce.2005.11.052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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