Article
Correlation between left ventricular mass and urinary sodium excretion in specific genotypes of CYP11B2.
Journal of hypertension - 1 Jun 2005
Isaji Mako, Mune Tomoatsu, Takada Nobuki, Yamamoto Yoritsuna, Suwa Tetsuya, Morita Hiroyuki, Takeda Jun, White Perrin C
Abstract excerpt
BACKGROUND: Aldosterone has essential roles in regulating intravascular volume and blood pressure, and is suggested to influence cardiac structure. However, the association of polymorphisms in the aldosterone synthase gene (CYP11B2) with hypertension or cardiac hypertrophy remains controversial. OBJECTIVE: To evaluate the distribution of polymorphisms in the CYP11B2 gene and the possible associations between...
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