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Article

Analysis of FcgammaRII gene polymorphisms in Wegener's granulomatosis.

Experimental and clinical immunogenetics - 1 Jan 1997

Edberg J C, Wainstein E, Wu J, Csernok E, Sneller M C, Hoffman G S, Keystone E C, Gross W L, Kimberly R P

Abstract excerpt

Fcgamma receptors (FcgammaRs) are potent initiators of proinflammatory reactions and tissue injury programs through the oxidative burst, degranulation and the production of a variety of proinflammatory cytokines. Direct experimental evidence indicates that translocation of ANCA target from intracellular granules to the neutrophil membrane and subsequent binding of ANCA enables FcgammaR-mediated neutrophil...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 9493787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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