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Article

Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutations.

Nucleic acids research - 15 Mar 1998

Liu W, Smith D I, Rechtzigel K J, Thibodeau S N, James C D

Abstract excerpt

Denaturing high performance liquid chromatography (DHPLC) has been described recently as a method for screening DNA samples for single nucleotide polymorphisms and inherited mutations. Thirty-eight DNAs, 22 of which were heterozygous for previously characterized rearranged transforming gene (RET) or cystic fibrosis transmembrane conductance regulator gene (CFTR) mutations or polymorphisms, were examined using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 9490783
DOI: 10.1093/nar/26.6.1396
PMCID: PMC147438

Genes

PTEN
RET
CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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