Article
Phenotypic difference between Bcg(r) and Bcg(s) macrophages is related to differences in protein-kinase-C-dependent signalling.
European journal of biochemistry - 1 Feb 1998
Olivier M, Cook P, Desanctis J, Hel Z, Wojciechowski W, Reiner N E, Skamene E, Radzioch D
Abstract excerpt
Mice of diverse genetic backgrounds may be classified as being either resistant or susceptible to infection with Mycobacteria. These phenotypes appear to be determined by a single gene on chromosome 1, the Bcg gene, and are expressed at the level of the macrophage in vitro. When compared to macrophages from mice of the susceptible phenotype (Bcg[s]), macrophages from mice of the resistant phenotype (Bcg[r]) show...
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