Article
Interleukin-10 production by lung macrophages in CBA xid mutant mice infected with Mycobacterium tuberculosis.
Immunology - 1 Jun 2005
Junqueira-Kipnis Ana Paula, Kipnis Andre, Henao Tamayo Marcela, Harton Marisa, Gonzalez Juarrero Mercedes, Basaraba Randall J, Orme Ian M
Abstract excerpt
Mice on the CBA inbred strain background expressing the well characterized mutation designated xid in the cytoplasmic signalling enzyme Bruton's protein kinase have been previously noted to illustrate shifts in T helper type 1 (Th1)/Th2 immunity which is underlined by an apparent failure to produce the regulatory cytokine interleukin-10. In the current study we examined if this extended to infection with...
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