Article
Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice.
The Journal of clinical investigation - 1 Mar 1998
Bezerra J A, Carrick T L, Degen J L, Witte D, Degen S J
Abstract excerpt
Hepatocyte growth factor-like protein (HGFL) is a liver-derived serum glycoprotein involved in cell proliferation and differentiation, and is proposed to have a fundamental role in embryogenesis, fertility, hematopoiesis, macrophage activation, and tissue repair. To assess the in vivo effects of total loss of HGFL, we generated mice with targeted disruption of the gene resulting in loss of the protein. Disruption...
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