Article
Activation of Met tyrosine kinase by hepatocyte growth factor is essential for internal organogenesis in Xenopus embryo.
Biochemical and biophysical research communications - 8 May 1997
Aoki S, Takahashi K, Matsumoto K, Nakamura T
Abstract excerpt
Hepatocyte growth factor (HGF) specifically activates Met tyrosine kinase receptor, leading to mitogenic, motogenic, and morphogenic responses in a wide variety of cells. To know a role of HGF in Xenopus embryogenesis, loss-of-function mutation was introduced by dominant expression of truncated t...
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