Characterization of seven genes affecting Caenorhabditis elegans hindgut development.

doi:10.1093/genetics/153.2.731

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Article

Characterization of seven genes affecting Caenorhabditis elegans hindgut development.

Genetics - 1 Oct 1999

Chamberlin H M, Brown K B, Sternberg P W, Thomas J H

Abstract excerpt

We have identified and characterized 12 mutations in seven genes that affect the development of the Caenorhabditis elegans hindgut. We find that the mutations can disrupt the postembryonic development of the male-specific blast cells within the hindgut, the hindgut morphology in both males and hermaphrodites, and in some cases, the expression of a hindgut marker in hermaphrodite animals. Mutations in several of...

Topics

Aging
Amino Acid Sequence
Animals
Caenorhabditis elegans
Digestive System
Disorders of Sex Development
Genes, Helminth
Genetic Complementation Test
Genetic Linkage
Helminth Proteins
Heterozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Molecular Sequence Data

Mutagenesis

Mutation

Mutation, Missense

Protein Structure, Secondary

Recombination, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 10511553
DOI: 10.1093/genetics/153.2.731
PMCID: PMC1460777

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-10511553-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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