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Article

Genetic control of vulval development in Caenorhabditis briggsae.

G3 (Bethesda, Md.) - 1 Dec 2012

Sharanya Devika, Thillainathan Bavithra, Marri Sujatha, Bojanala Nagagireesh, Taylor Jon, Flibotte Stephane, Moerman Donald G, Waterston Robert H, Gupta Bhagwati P

Abstract excerpt

The nematode Caenorhabditis briggsae is an excellent model organism for the comparative analysis of gene function and developmental mechanisms. To study the evolutionary conservation and divergence of genetic pathways mediating vulva formation, we screened for mutations in C. briggsae that cause the egg-laying defective (Egl) phenotype. Here, we report the characterization of 13 genes, including three that are...

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PMID: 23275885
DOI: 10.1534/g3.112.004598
PMCID: PMC3516484

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