Article
Genetic control of vulval development in Caenorhabditis briggsae.
G3 (Bethesda, Md.) - 1 Dec 2012
Sharanya Devika, Thillainathan Bavithra, Marri Sujatha, Bojanala Nagagireesh, Taylor Jon, Flibotte Stephane, Moerman Donald G, Waterston Robert H, Gupta Bhagwati P
Abstract excerpt
The nematode Caenorhabditis briggsae is an excellent model organism for the comparative analysis of gene function and developmental mechanisms. To study the evolutionary conservation and divergence of genetic pathways mediating vulva formation, we screened for mutations in C. briggsae that cause the egg-laying defective (Egl) phenotype. Here, we report the characterization of 13 genes, including three that are...
Topics
- Animals
- Animals, Genetically Modified
- Caenorhabditis
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Nucleus
- Chromosome Mapping
- Drosophila Proteins
- Female
- Genetic Linkage