Article
Cell fates and fusion in the C. elegans vulval primordium are regulated by the EGL-18 and ELT-6 GATA factors -- apparent direct targets of the LIN-39 Hox protein.
Development (Cambridge, England) - 1 Nov 2002
Koh Kyunghee, Peyrot Sara M, Wood Cricket G, Wagmaister Javier A, Maduro Morris F, Eisenmann David M, Rothman Joel H
Abstract excerpt
Development of the vulva in C. elegans is mediated by the combinatorial action of several convergent regulatory inputs, three of which, the Ras, Wnt and Rb-related pathways, act by regulating expression of the lin-39 Hox gene. LIN-39 specifies cell fates and regulates cell fusion in the mid-body region, leading to formation of the vulva. In the lateral seam epidermis, differentiation and cell fusion have been...
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- Animals
- Binding Sites
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Differentiation