Article
Cell fates and fusion in the C. elegans vulval primordium are regulated by the EGL-18 and ELT-6 GATA factors -- apparent direct targets of the LIN-39 Hox protein.
Development (Cambridge, England) - 1 Nov 2002
Koh Kyunghee, Peyrot Sara M, Wood Cricket G, Wagmaister Javier A, Maduro Morris F, Eisenmann David M, Rothman Joel H
Abstract excerpt
Development of the vulva in C. elegans is mediated by the combinatorial action of several convergent regulatory inputs, three of which, the Ras, Wnt and Rb-related pathways, act by regulating expression of the lin-39 Hox gene. LIN-39 specifies cell fates and regulates cell fusion in the mid-body...
Topics
- Animals
- Binding Sites
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Differentiation
- Cell Fusion
- DNA-Binding Proteins
- Dimerization
- Enhancer Elements, Genetic
- Female
- GATA Transcription Factors
- Green Fluorescent Proteins
- Helminth Proteins