Article

Prolonging somatic cell proliferation through constitutive hox gene expression in C. elegans

2023-05-18

Abstract excerpt

hox genes encode a conserved family of homeobox transcription factors that are essential to determine the identity of body segments during embryogenesis and maintain adult somatic stem cells competent to regenerate organs. In contrast to higher organisms, somatic cells in C. elegans irreversibly exit the cell cycle after completing their cell lineage, and the adult soma cannot regenerate. Here, we show that hox ge...

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Literature Corpus work: 8d527998-aac1-513b-a223-a2282e396b05
DOI: 10.21203/rs.3.rs-2921597/v1

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