Article
Linkage analysis suggests a region of importance for multiple sclerosis in 3p14-13.
Genes and immunity - 1 Dec 2001
Dai Y, Xu C, Holmberg M, Oturai A, Fredrikson S, Sandberg-Wollheim M, Laaksonen M, Spurkland A, Myhr K M, Ryder L P, Sorensen P S, Svejgaard A, Hillert J
Abstract excerpt
Four genomic screens for linkage in multiple sclerosis (MS) have been reported. They confirmed the established role of the human leucocyte antigen (HLA) complex genes in MS and, in addition, suggested the importance of a few other chromosomal segments. Here we report evidence for the importance of 3p14-13 region identified by suggestive linkage in genomic screens from Canada and the United Kingdom. When studying...
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