Article
Low frequency of TSG101/CC2 gene alterations in invasive human breast cancers.
Oncogene - 5 Feb 1998
Wang Q, Driouch K, Courtois S, Champème M H, Bièche I, Treilleux I, Briffod M, Rimokh R, Magaud J P, Curmi P, Lidereau R, Puisieux A
Abstract excerpt
Large intragenic deletions of the TSG101/CC2 gene were recently reported in seven of 15 primary metastatic breast cancers. Although the number of samples was small, this observation suggested that TSG101/CC2 alterations were a major event in breast carcinogenesis. To study the frequency of these deletions in invasive breast cancers we analysed 189 primary invasive breast tumours and 59 breast cancer metastases....
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