Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of BRCA1, TP53, and TSG101 germline mutations in German breast and/or ovarian cancer families.

Cancer genetics and cytogenetics - 15 Oct 2002

Balz Vera, Prisack Hans Bernd, Bier Henning, Bojar Hans

Abstract excerpt

About 5%-10% of breast cancers are considered to be hereditary and associated with germline mutations of specific genes. As yet, the most frequently affected genes identified are BRCA1 and BRCA2, but also other genes such as TP53 are supposed to influence the predisposition toward breast cancer. In the present study, we analyzed patients of 19 German families with early onset breast cancer and/or a family history...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to BRCA1 Protein
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endosomal Sorting Complexes Required for Transport

Share to Germ-Line Mutation

Share to Germany

Share to Ovarian Neoplasms

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 12505256
DOI: 10.1016/s0165-4608(02)00601-5

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of BRCA1, TP53, and TSG101 germline mutations in German breast and/or ovarian cancer families.PMID 12505256Read ↗

Mutation analysis of BRCA1 and BRCA2 in Turkish cancer families: a novel mutation BRCA2 3414del4 found in male breast cancer.Semantic proximity Read ↗

Mutation screening of BRCA1 using PTT and LOH analysis at 17q21 in breast carcinomas from familial and non-familial cases.Semantic proximity Read ↗

Founding BRCA1 mutations in hereditary breast and ovarian cancer in southern Sweden.Semantic proximity Read ↗

BRCA1 mutations in German breast-cancer families.Semantic proximity Read ↗

Multiple truncated transcripts of TSG101 in gastrointestinal cancers.Semantic proximity Read ↗

Moderate frequency of BRCA1 and BRCA2 germ-line mutations in Scandinavian familial breast cancer.Semantic proximity Read ↗

Screening for TP53 mutations in patients and tumours from 109 Swedish breast cancer families.Semantic proximity Read ↗

BRCA1 germline mutational spectrum in Italian families from Tuscany: a high frequency of novel mutations.Semantic proximity Read ↗

Identification of seven new BRCA1 germline mutations in Italian breast and breast/ovarian cancer families.Semantic proximity Read ↗

Aberrant splicing but not mutations of TSG101 in human breast cancer.Semantic proximity Read ↗

Role of TSG101 in uterine cervix cancer.Semantic proximity Read ↗

Screening for mutations in exon 11 of the BRCA1 gene in 70 Italian breast and ovarian cancer patients by protein truncation test.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.