Article
Analysis of expression and structure of the TSG101 gene in cervical cancer cells.
International journal of molecular medicine - 1 May 2010
Broniarczyk J, Olejnik-Schmidt A K, Luczak M W, Schmidt M T, Dabrowski M, Józefiak A, Kedzia W, Kwasniewska A, Gozdzicka-Józefiak A
Abstract excerpt
Human papillomavirus (HPV)-mediated transformation of human epithelial cells has been recognized as a multi-step process in which additional unknown factors and (epi)genetic events are required. The tumor susceptibility gene 101 (TSG101) was discovered in mouse NIH3T3 fibroblast cells as a gene whose functional knockout leads to transformation. TSG101 protein is involved in a variety of important biological...
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