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Article

Overexpression of tumor susceptibility gene TSG101 in human papillary thyroid carcinomas.

Oncogene - 18 Jul 2002

Liu Rue-Tsuan, Huang Chao-Cheng, You Huey-Ling, Chou Fong-Fu, Hu Chih-Chi Andrew, Chao Fang-Ping, Chen Ching-Mei, Cheng Jiin-Tsuey

Abstract excerpt

Functional inactivation of tumor susceptibility gene tsg101 leads to cellular transformation and tumorigenesis in mice. While human TSG101 is located in a region where frequent loss of heterozygosity can be detected in a variety of cancers, no genomic deletion in TSG101 gene has been reported, casting a doubt on the role of TSG101 as a classical tumor suppressor. Some studies have revealed that TSG101 is a...

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Share to Antibody Specificity
Share to Carcinoma, Papillary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endosomal Sorting Complexes Required for Transport

Share to In Situ Hybridization

Share to RNA, Neoplasm

Share to Thyroid Neoplasms

Share to Transcriptional Activation

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Source

Identifiers

PMID: 12101421
DOI: 10.1038/sj.onc.1205612

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Overexpression of tumor susceptibility gene TSG101 in human papillary thyroid carcinomas.PMID 12101421Read ↗

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Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells.Semantic proximity Read ↗

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TSG101 is not mutated in lung cancer but a shortened transcript is frequently expressed in small cell lung cancer.Semantic proximity Read ↗

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