Article
Hypermethylation of the TSLC1 gene promoter in primary gastric cancers and gastric cancer cell lines.
Japanese journal of cancer research : Gann - 1 Aug 2002
Honda Teiichiro, Tamura Gen, Waki Takayoshi, Jin Zhe, Sato Kiyoshi, Motoyama Teiichi, Kawata Sumio, Kimura Wataru, Nishizuka Satoshi, Murakami Yoshinori
Abstract excerpt
The TSLC1 (tumor suppressor in lung cancer-1) gene is a novel tumor suppressor gene on chromosomal region 11q23.2, and is frequently inactivated by concordant promoter hypermethylation and loss of heterozygosity (LOH) in non-small cell lung cancer (NSCLC). Because LOH on 11q has also been observe...
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