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Article

The phenotype of SLE associated with complete deficiency of complement isotype C4A.

Journal of clinical immunology - 1 Jan 1998

Welch T R, Brickman C, Bishof N, Maringhini S, Rutkowski M, Frenzke M, Kantor N

Abstract excerpt

Complete deficiency of the complement C4A isotype is a known genetic risk factor for systemic lupus erythematosus (SLE). The disease phenotype of C4A-deficient patients has never been defined. Among 200 patients with SLE from five centers, 18 (9%) with C4A deficiency were identified. These individuals were compared to those who were C4A replete with regard to a series of clinical and serologic features. The only...

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Identifiers

PMID: 9475353
DOI: 10.1023/a:1023287820786

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The phenotype of SLE associated with complete deficiency of complement isotype C4A.PMID 9475353Read ↗

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