C4 phenotypes in IgA nephropathy: disease progression associated with C4A deficiency but not with C4 isotype concentrations.

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Article

C4 phenotypes in IgA nephropathy: disease progression associated with C4A deficiency but not with C4 isotype concentrations.

Clinical nephrology - 1 Mar 1996

Wopenka U, Thysell H, Sjöholm A G, Truedsson L

Abstract excerpt

IgA nephropathy (IgAN) is a common glomerular disease and is thought to have an immunological origin which may involve complement-mediated pathogenic mechanisms. We performed C4 phenotyping and C4 isotype quantification in 93 IgAN patients in Southern Sweden. Phenotype frequencies did not deviate...

Topics

Adolescent
Adult
Aged
Biomarkers
Child
Complement C4
Complement C4a
Disease Progression
Enzyme-Linked Immunosorbent Assay
Female
Follow-Up Studies
Glomerulonephritis, IGA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Incidence

Kidney Failure, Chronic

Male

Middle Aged

Phenotype

Source

Open in PubMed

Identifiers

PMID: 8706353

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8706353-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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