Complement component C4 deficiencies and gene alterations in patients with systemic lupus erythematosus.

doi:10.1111/j.1744-313x.1993.tb00091.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Complement component C4 deficiencies and gene alterations in patients with systemic lupus erythematosus.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Feb 1993

Fan Q, Uring-Lambert B, Weill B, Gautreau C, Menkes C J, Delpech M

Abstract excerpt

Deficiency of complement component C4 is considered playing a role in the genetic predisposition for systemic lupus erythematosus (SLE). The purpose of this study was to characterize the genomic alterations of the C4 and CYP21 genes in 40 caucasoid patients with SLE by C4 allotyping and by RFLP a...

Topics

Alleles
Complement C4
Gene Conversion
Gene Deletion
Humans
Lupus Erythematosus, Systemic
Multigene Family
Polymorphism, Restriction Fragment Length
Steroid 21-Hydroxylase

Source

Open in PubMed

Identifiers

PMID: 8095158
DOI: 10.1111/j.1744-313x.1993.tb00091.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8095158-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics