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Article

Homozygous C4A deficiency in systemic lupus erythematosus: analysis of patients from a defined population.

Clinical genetics - 1 Dec 1990

Sturfelt G, Truedsson L, Johansen P, Jonsson H, Nived O, Sjöholm A G

Abstract excerpt

Homozygous C4A deficiency was found at a prevalence of 16% (13/80 patients) in systemic lupus erythematosus (SLE). The patients represented all diagnosed cases retrieved from a defined population in Southern Sweden, which minimizes the influence of patient selection. Photosensitivity was more common among C4A-deficient patients than among other SLE patients (p less than 0.05). Otherwise, clinical features were...

Topics

Antibodies, Antinuclear
Complement Activation
Complement C4a
Complement C4b
Female
Homozygote
Humans
Lupus Erythematosus, Systemic
Male
Middle Aged
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prospective Studies

Risk Factors

Source

Identifiers

PMID: 2289315
DOI: 10.1111/j.1399-0004.1990.tb03608.x

Genes

SSB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2289315-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Homozygous C4A deficiency in systemic lupus erythematosus: analysis of patients from a defined population.PMID 2289315Read ↗

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