Article
Three distinct profiles of serum complement C4 proteins in pediatric systemic lupus erythematosus (SLE) patients: tight associations of complement C4 and C3 protein levels in SLE but not in healthy subjects.
Advances in experimental medicine and biology - 1 Jan 2006
Wu Yee-Ling, Higgins Gloria C, Rennebohm Robert M, Chung Erwin K, Yang Yan, Zhou Bi, Nagaraja Haikady N, Birmingham Dan J, Rovin Brad H, Hebert Lee A, Yu C Yung
Abstract excerpt
The serial changes of serum complement proteins C4 and C3 in SLE were characterized in 33 pediatric SLE patients with defined C4 genotypes. Three distinct groups of C4 protein profiles were observed. The first group was characterized by persistently low C4 levels (<10 mg/dL) throughout the course...
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