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Article

The apbE gene encodes a lipoprotein involved in thiamine synthesis in Salmonella typhimurium.

Journal of bacteriology - 1 Feb 1998

Beck B J, Downs D M

Abstract excerpt

Thiamine pyrophosphate is an essential cofactor that is synthesized de novo in Salmonella typhimurium. The biochemical steps and gene products involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine (HMP) moiety of thiamine have yet to be elucidated. We have isolated mutations in a new locus (Escherichia coli open reading frame...

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Identifiers

PMID: 9473043
DOI: 10.1128/JB.180.4.885-891.1998
PMCID: PMC106968

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The apbE gene encodes a lipoprotein involved in thiamine synthesis in Salmonella typhimurium.PMID 9473043Read ↗

Genetic analysis of metabolic crosstalk and its impact on thiamine synthesis in Salmonella typhimurium.Semantic proximity Read ↗

The stm4066 gene product of Salmonella enterica serovar Typhimurium has aminoimidazole riboside (AIRs) kinase activity and allows AIRs to satisfy the thiamine requirement of pur mutant strains.Semantic proximity Read ↗

Evidence that rseC, a gene in the rpoE cluster, has a role in thiamine synthesis in Salmonella typhimurium.Semantic proximity Read ↗

Mutations in apbC (mrp) prevent function of the alternative pyrimidine biosynthetic pathway in Salmonella typhimurium.Semantic proximity Read ↗

Evidence for a new, oxygen-regulated biosynthetic pathway for the pyrimidine moiety of thiamine in Salmonella typhimurium.Semantic proximity Read ↗

Plasticity in the purine-thiamine metabolic network of Salmonella.Semantic proximity Read ↗

Identification and characterization of an operon in Salmonella typhimurium involved in thiamine biosynthesis.Semantic proximity Read ↗

Synthesis of thiamine in Salmonella typhimurium independent of the purF function.Semantic proximity Read ↗

A novel involvement of the PurG and PurI proteins in thiamine synthesis via the alternative pyrimidine biosynthetic (APB) pathway in Salmonella typhimurium.Semantic proximity Read ↗

Altered pathway routing in a class of Salmonella enterica serovar Typhimurium mutants defective in aminoimidazole ribonucleotide synthetase.Semantic proximity Read ↗

Lesions in the nuo operon, encoding NADH dehydrogenase complex I, prevent PurF-independent thiamine synthesis and reduce flux through the oxidative pentose phosphate pathway in Salmonella enterica serovar typhimurium.Semantic proximity Read ↗

Analysis of ThiC variants in the context of the metabolic network of Salmonella enterica.Semantic proximity Read ↗

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