Article
Identification and characterization of an operon in Salmonella typhimurium involved in thiamine biosynthesis.
Journal of bacteriology - 1 Aug 1997
Petersen L A, Downs D M
Abstract excerpt
Thiamine pyrophosphate (TPP) is synthesized de novo in Salmonella typhimurium and is a required cofactor for many enzymes in the cell. Five kinase activities have been implicated in TPP synthesis, which involves joining a 4-methyl-5-(beta-hydroxyethyl)thiazole (THZ) moiety and a 4-amino-5-hydroxy...
Topics
- Amino Acid Sequence
- Base Sequence
- Chromosome Mapping
- DNA, Bacterial
- Gene Expression Regulation, Bacterial
- Gene Expression Regulation, Enzymologic
- Molecular Sequence Data
- Molecular Structure
- Mutagenesis
- Mutation
- Operon
- Phosphotransferases (Alcohol Group Acceptor)
- Phosphotransferases (Phosphate Group Acceptor)
- Polymerase Chain Reaction
- Pyrimidines
- Salmonella typhimurium
- Sequence Homology, Amino Acid
- Thiamine
