Article
Frequent detection of mutations in the 5' flanking region of the prostate-specific antigen gene in female breast cancer.
European journal of cancer (Oxford, England : 1990) - 1 Oct 1997
Tsuyuki D, Grass L, Diamandis E P
Abstract excerpt
Prostate-specific antigen (PSA) is expressed in normal, hyperplastic and cancerous female breast tissue. Expression is regulated by steroid hormones. Some breast tumours produce very high levels of PSA, while other do not express any PSA. In this study, we selected three primary breast tumours wh...
Topics
- Base Sequence
- Breast Neoplasms
- Exons
- Female
- Gene Deletion
- Gene Expression Regulation, Neoplastic
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Prostate-Specific Antigen
- Sequence Analysis