Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a cullin homology region in a subunit of the anaphase-promoting complex.

Science (New York, N.Y.) - 20 Feb 1998

Yu H, Peters J M, King R W, Page A M, Hieter P, Kirschner M W

Abstract excerpt

The anaphase-promoting complex is composed of eight protein subunits, including BimE (APC1), CDC27 (APC3), CDC16 (APC6), and CDC23 (APC8). The remaining four human APC subunits, APC2, APC4, APC5, and APC7, as well as human CDC23, were cloned. APC7 contains multiple copies of the tetratrico peptid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cell Cycle
Share to Cell Cycle Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cloning, Molecular

Share to APC gene

Share to Helminth Proteins

Share to Ligases

Share to Molecular Sequence Data

Source

Identifiers

PMID: 9469815
DOI: 10.1126/science.279.5354.1219

Genes

APC2
CDC23
CDC16
CDC27
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9469815-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a cullin homology region in a subunit of the anaphase-promoting complex.PMID 9469815Read ↗

The anaphase-promoting complex: A key mitotic regulator associated with somatic mutations occurring in cancer.Semantic proximity Read ↗

Cullin Family Proteins and Tumorigenesis: Genetic Association and Molecular MechanismsSemantic proximity Read ↗

A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression.Semantic proximity Read ↗

RCS1, a substrate of APC/C, controls the metaphase to anaphase transition.Semantic proximity Read ↗

Identification of BIME as a subunit of the anaphase-promoting complex.Semantic proximity Read ↗

Genomic evolution and complexity of the Anaphase-promoting Complex (APC) in land plants.Semantic proximity Read ↗

Human CDC23: cDNA cloning, mapping to 5q31, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias.Semantic proximity Read ↗

CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.Semantic proximity Read ↗

Alterations of anaphase-promoting complex genes in human colon cancer cells.Semantic proximity Read ↗

Identification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulation.Semantic proximity Read ↗

The Cdc20 homolog, FZY-1, and its interacting protein, IFY-1, are required for proper chromosome segregation in Caenorhabditis elegans.Semantic proximity Read ↗

The destruction box of the cyclin Clb2 binds the anaphase-promoting complex/cyclosome subunit Cdc23.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.