Article
Combinatorial library diversity: probability assessment of library populations.
Nucleic acids research - 15 Feb 1998
Ward B, Juehne T
Abstract excerpt
A method is described for measuring the diversity of combinatorial oligonucleotide libraries that entails extrapolating the base composition of a co-synthesized model library (dNC, N = A, C, G, T) to that of a multibase library template. The base composition of dNC was measured by HPLC. The ability of dNC to predict the base composition of a multibase library template was corroborated by measuring the composition...
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