Article
Allelic loss on chromosome 10q in human lung cancer: association with tumour progression and metastatic phenotype.
British journal of cancer - 1 Jan 1998
Petersen S, Wolf G, Bockmühl U, Gellert K, Dietel M, Petersen I
Abstract excerpt
We analysed 78 carcinomas of the lung for allelic losses on chromosome 10q. The tumours were of different stage and grade and comprised 22 small-cell lung carcinomas (SCLC), 40 squamous cell carcinomas (SCC), 11 adenocarcinomas, four large-cell carcinomas and one carcinoid. They were investigated by six polymorphic markers located between 10q21 and 10qter. We observed a high incidence of loss of heterozygosity...
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