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Article

The MXI1 tumor suppressor gene is not mutated in primary prostate cancer.

Oncology reports - 1 Jan 2000

Kuczyk M A, Serth J, Bokemeyer C, Schwede J, Herrmann R, Machtens S, Grünewald V, Höfner K, Jonas U

Abstract excerpt

For prostate cancer, allelic deletions from the long arm of chromosome 10 (#10q23-25), the locus of the putative tumor suppressor gene MXI1 (#10q24-25), have been identified as a frequently occurring genetic event. During the development of several human malignancies, the c-myc proto-oncogene has been identified to enhance cellular transformation, mitogenesis and cell proliferation. The MXI1 gene, belonging to...

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Source

Identifiers

PMID: 9458379

Genes

MXI1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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The MXI1 tumor suppressor gene is not mutated in primary prostate cancer.PMID 9458379Read ↗

Mutation of the MXI1 gene in prostate cancer.Semantic proximity Read ↗

Commonly occurring loss and mutation of the MXI1 gene in prostate cancer.Semantic proximity Read ↗

Loss of the chromosomal region 10q23-25 in prostate cancer.Semantic proximity Read ↗

Mxi1 tumor suppressor gene is not mutated in primary pancreatic adenocarcinoma.Semantic proximity Read ↗

Molecular analysis of PTEN and MXI1 in primary bladder carcinoma.Semantic proximity Read ↗

Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth.Semantic proximity Read ↗

PTEN/MMAC1 is infrequently mutated in pT2 and pT3 carcinomas of the prostate.Semantic proximity Read ↗

I105V polymorphism and promoter methylation of the GSTP1 gene in prostate adenocarcinoma.Semantic proximity Read ↗

Alterations in PMS2, MSH2 and MLH1 expression in human prostate cancer.Semantic proximity Read ↗

Down-regulation of the KAI1 metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss.Semantic proximity Read ↗

Loss of heterozygosity in the MXI1 gene is a frequent occurrence in melanoma.Semantic proximity Read ↗

Microsatellite instability and deletion analysis of chromosome 10 in human prostate cancer.Semantic proximity Read ↗

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