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Article

Loss of the chromosomal region 10q23-25 in prostate cancer.

Cancer research - 1 Nov 1995

Gray I C, Phillips S M, Lee S J, Neoptolemos J P, Weissenbach J, Spurr N K

Abstract excerpt

Loss of the chromosomal region 10q23-25 is a frequent event in the progression of prostate adenocarcinoma. A candidate tumor suppressor gene from this region, Mxi1 at 10q25, has recently been shown to be mutated in a small number of prostate tumors. To more strictly define those regions of 10q loss that are likely to be involved in tumor advancement, we have constructed a detailed deletion map spanning 10q23-25...

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PMID: 7585509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Loss of the chromosomal region 10q23-25 in prostate cancer.PMID 7585509Read ↗

Commonly occurring loss and mutation of the MXI1 gene in prostate cancer.Semantic proximity Read ↗

Mutation of the MXI1 gene in prostate cancer.Semantic proximity Read ↗

Allelic loss on chromosome 10 in prostate adenocarcinoma.Semantic proximity Read ↗

Allelic losses at loci on chromosome 10 are associated with metastasis and progression of human prostate cancer.Semantic proximity Read ↗

The MXI1 tumor suppressor gene is not mutated in primary prostate cancer.Semantic proximity Read ↗

Loss of a small region around the PTEN locus is a major chromosome 10 alteration in prostate cancer xenografts and cell lines.Semantic proximity Read ↗

Distinct areas of allelic loss on chromosomal regions 10p and 10q in human prostate cancer.Semantic proximity Read ↗

Clinical significance of chromosome 8p, 10q, and 16q deletions in prostate cancerSemantic proximity Read ↗

Microsatellite instability and deletion analysis of chromosome 10 in human prostate cancer.Semantic proximity Read ↗

Allelic loss on chromosomes 8p, 22q and 18q (DCC) in human prostate cancer.Semantic proximity Read ↗

Allelic loss of chromosomes 16q and 10q in human prostate cancer.Semantic proximity Read ↗

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