Loss of the chromosomal region 10q23-25 in prostate cancer.

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Article

Loss of the chromosomal region 10q23-25 in prostate cancer.

Cancer research - 1 Nov 1995

Gray I C, Phillips S M, Lee S J, Neoptolemos J P, Weissenbach J, Spurr N K

Abstract excerpt

Loss of the chromosomal region 10q23-25 is a frequent event in the progression of prostate adenocarcinoma. A candidate tumor suppressor gene from this region, Mxi1 at 10q25, has recently been shown to be mutated in a small number of prostate tumors. To more strictly define those regions of 10q lo...

Topics

Aged
Aged, 80 and over
Alleles
Base Sequence
Basic Helix-Loop-Helix Transcription Factors
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 10
DNA, Neoplasm
DNA, Satellite
DNA-Binding Proteins
Fluorescence
Genes, Tumor Suppressor
Genetic Markers
Heterozygote
Humans
Male
Middle Aged

Source

Open in PubMed

Identifiers

PMID: 7585509

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7585509-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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