Article
Triplet repeat polymorphism within the NOTCH4 gene located near the junction of the HLA class II and class III regions in narcolepsy.
Tissue antigens - 1 Dec 1997
Ando A, Shigenari A, Naruse T K, Sugaya K, Juji T, Honda Y, Ikemura T, Inoko H
Abstract excerpt
A polymorphic (CTG)n microsatellite repeat was found in the signal peptide domain of the NOTCH4 gene located near the junction of the class II and class III regions of the human major histocompatibility complex. This gene belongs to a multigene family of NOTCH originally identified as a differential factor of neuronal cells. To ascertain whether the NOTCH4 gene is involved in the development of neurogenic...
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