Article
Triplet repeat polymorphism in the NOTCH4 gene with the human major histocompatibility complex in a healthy population and patients with a salivary gland tumor in Japan.
Tissue antigens - 1 Jul 1997
Ando A, Sugaya K, Shigenari A, Naruse T K, Horiuchi M, Shiina T, Kawata H, Chen L, Ikemura T, Inoko H
Abstract excerpt
The NOTCH4 gene, the human counterpart of the mouse mammary tumor gene, int-3, has been recently localized near the boundary of the HLA class II and class III regions. This gene is one of candidates for development of salivary gland tumor. Microsatellite polymorphism of (CTG)n repeat in the signal peptide domain of NOTCH4 was analyzed in Japanese including the patients with salivary gland tumor. Four alleles...
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