Article
Efficient localization of mutations by interval haplotype analysis.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 1998
Neuhaus I M, Beier D R
Abstract excerpt
We have developed a mathematical algorithm to implement a method for localizing mutations using haplotype analysis. Our strategy infers haplotypes based on the determination of genotypes of a proximal and a distal marker for 21 chromosomal intervals distributed across the mouse genome (corresponding to two intervals for Chromosomes (Chrs) 1 and 2 and one for the remaining 17 autosomes). To simulate the analysis...
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