Article
A comprehensive mouse IBD database for the efficient localization of quantitative trait loci.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2006
Cervino Alessandra C L, Gosink Mark, Fallahi Mohammad, Pascal Bruce, Mader Christopher, Tsinoremas Nicholas F
Abstract excerpt
Traditional fine-mapping approaches in mouse genetics that go from a linkage region to a candidate gene are very costly and time consuming. Shared ancestry regions, along with the combination of genetics and genomics approaches, provide a powerful tool to shorten the time and effort required to identify a causative gene. In this article we present a novel methodology that predicts IBD (identical by descent)...
Topics
- Algorithms
- Animals
- Databases, Genetic
- Mice
- Mice, Inbred Strains
- Polymorphism, Single Nucleotide
- Quantitative Trait Loci
