Article
Comparative analysis of haplotype association mapping algorithms.
BMC bioinformatics - 9 Feb 2006
McClurg Phillip, Pletcher Mathew T, Wiltshire Tim, Su Andrew I
Abstract excerpt
BACKGROUND: Finding the genetic causes of quantitative traits is a complex and difficult task. Classical methods for mapping quantitative trail loci (QTL) in miceuse an F2 cross between two strains with substantially different phenotype and an interval mapping method to compute confidence intervals at each position in the genome. This process requires significant resources for breeding and genotyping, and the...
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